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AEON Biopharma Reports Disappointing Interim Phase 2 Results of Migraine Preventive ABP-450
Newly announced preliminary top-line results from a planned interim analysis of a phase 2 study (NCT04845178) showed that treatment with ABP-450 (AEON Biopharma) did not meet its p...
Depression Predisposes Parkinson Disease, Associated With Worse Disease Severity
Using data from more than 430,000 participants with 14.1 years of follow-up, findings from a recently published study showed that depression is common in patients with Parkinson di...
NeurologyLive® Friday 5 — May 10, 2024
Welcome to NeurologyLive®'s Friday 5! Every week, the staff compiles 5 highlights of NeurologyLive®'s widespread coverage in neurology, ranging from newsworthy study findings and...
FDA Grants Breakthrough Therapy Designation for AOC 1001 in Myotonic Dystrophy Type 1
Sarah Boyce(Credit: Avidity)According to a recent announcement, the FDA has granted breakthrough therapy designation to AOC 1001 (Avidity Biosciences), an investigational treatment...
CSF Anti-DAGLA Autoantibodies Identified as Potential Biomarker of Rapidly Progressive Cerebellitis
Kurt-Wolfram Sühs, MD(Credit: Hannover Medical School)In a small-scale study published in the Journal of Neurology, Neurosurgery & Psychiatry, investigators identified diacylglyce...
Basal Ganglia Activity Associated With REM Sleep Behavior Disorder in Parkinson Disease
Jian-Guo Zhang, MD, PhD(Credit: Capital Medical University)Newly published in the Journal of Neurology, Neurosurgery and Psychiatry, findings showed that basal ganglia activities a...
Improvements in Neurological Assessments and Decreased Biological Age Seen With Alzheimer Agent Bezisterim
In a randomized, placebo-controlled trial, bezisterim (BioVie), an oral, small molecule, blood-brain permeable compound in development for Alzheimer disease (AD), demonstrated pote...
Alkermes Initiates Phase 2 Vibrance-1 Trial of Narcolepsy Agent ALKS 2680
Craig Hopkinson, MD(Credit: LinkedIn)According to a recent announcement, Alkermes has initiated its randomized, double-blind, dose-range-finding, placebo-controlled phase 2 Vibranc...