老年心梗合并高出血风险：完全血运重建 vs. 仅罪犯血管血运重建，孰优孰劣?
高出血风险(HBR)患者预后较差，尽管随机临床试验和荟萃分析清楚地表明，心肌梗死合并多血管疾病患者的完全血运重建术与更好的临床结果相关，但这是否可以推断到心肌梗死合并多血管疾病的HBR...
AEON Biopharma Reports Disappointing Interim Phase 2 Results of Migraine Preventive ABP-450
Newly announced preliminary top-line results from a planned interim analysis of a phase 2 study (NCT04845178) showed that treatment with ABP-450 (AEON Biopharma) did not meet its p...
SAGE-324/BIIB124 Significantly Reduces Upper Limb Tremor in Phase 2 KINETIC Trial
Helen Colquhoun, MD(Credit: LinkedIn)Recently published in Movement Disorders, results from the double-blind, randomized, placebo-controlled, phase 2 KINETIC trial (NCT04305275) as...
Anesthesiology丨麻醉诱导中的脑电图生物标志物可识别术后谵妄风险的易感患者
术后神经认知障碍是一种复杂的疾病，包括术后谵妄(POD)和术后神经认知功能障碍。高达50%的老年患者在手术干预后出现POD，这与发生长期不良结局的风险相关。由于患者仅表现为运动功能减退，导致P...
Early Treatment Response and Safety Profile of AXS-05 in Phase 3 ACCORD Trial: Anton P. Porsteinsson, MD
WATCH TIME: 6 minutes'It's important because when patients finally seek treatment for agitation and aggression that’s been going on for quite a while and has gotten to a critical ...
Understanding the Root of REM Behavior Disorder and Other Parasomnias
Parasomnias are sleep disorders that involve abnormal behaviors, emotional experiences, perceptions, and dream activity, occurring during specific sleep stages or sleep-wake transi...
Negative Myoclonus Associated With Severe Motor Implications in Progressive Myoclonus Ataxia
Marina A.J. Tijssen, MD, PhD(Credit: University of Groningen)In a newly published study in Movement Disorders, patients with progressive myoclonus ataxia (PMA) affected by negative...
NeurologyLive® Friday 5 — May 10, 2024
Welcome to NeurologyLive®'s Friday 5! Every week, the staff compiles 5 highlights of NeurologyLive®'s widespread coverage in neurology, ranging from newsworthy study findings and...
ALS Candidate PrimeC Shows Greater Treatment Effect in High-Risk ALS
Jeremy M. Shefner, MD, PhDNewly announced analyses from the phase 2b PARADIGM trial (NCT05357950) showed that treatment with PrimeC (NeuroSense), an investigational agent made up o...
